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What is Anti Phospolipid Ab, IgG, IgM?

Antiphospholipid antibody testing may be ordered when a patient has symptoms suggestive of a thrombotic episode, such as pain and swelling in the extremities, shortness of breath, and headaches. It also may be ordered when a woman has had recurrent miscarriages and/or as a follow-up to a prolonged PTT test. When one of the tests is positive, it may be repeated several weeks later to determine whether the antibody is temporary or persistent. Antiphospholipid testing may be done when clinical signs suggest the presence of antiphospholipid syndrome. When a patient with an autoimmune disorder tests negative for antiphospholipid antibodies, one or more of the tests may be ordered in the future to screen for the development of an antiphospholipid antibody.


Purpose of Test

Cardiolipin antibody testing may be ordered when a patient has symptoms suggestive of a thrombotic episode, such as pain and swelling in the extremities, shortness of breath, or headaches. It may also be ordered when a woman has had recurrent miscarriages, and/ or ordered along with lupus anticoagulant testing as a follow-up to a prolonged PTT test. When an IgG, IgM, and/ or IgA cardiolipin antibody is detected, then it may be repeated several weeks later to determine whether the antibody is temporary or persistent. Cardiolipin (anionic phospholipid) has been widely used for the detection of these antibodies. For the diagnosis of SLE , in evaluation of inappropriate blood clot formation & recurrent abortions.


Test of Result Interpretation

  • IgG: Normal: < 10, Elevated: >/= 10 GPL U/ml
  • IgM: Normal: < 7, Elevated: >/= 7MPL U/ml.

Preparation

No preparation required can collect the blood sample at any time.


Turnaround Time

8 Hrs